Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI7F1), TrueMAB
인간 NAGA 단백질을 인식하는 Mouse Monoclonal Antibody (OTI7F1). Western blot에 최적화된 TrueMAB 형식으로, 고순도 친화 크로마토그래피 정제. PBS, BSA, 글리세롤 기반 안정화 버퍼로 구성되어 -20°C에서 보관 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F1 |
| Immunogen | Full length human recombinant protein of human NAGA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411-amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown. The NAGA gene encodes alpha-N-acetylgalactosaminidase, a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates. Located on human chromosome 22q13.2, defects in NAGA cause Schindler disease (types I, II, and III), also known as NAGA deficiency. These disorders vary in severity, with type I being the most severe and type II (Kanzaki disease) characterized by mild intellectual impairment and angiokeratoma corporis diffusum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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