Thermo Fisher Scientific ZEB1 Polyclonal Antibody
ZEB1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 비결합(Unconjugated) 액상 형태이며 4°C에서 보관합니다. 인간 ZEB1 단백질(850-900 aa) 영역을 면역원으로 제작되었습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 850 and 900 of Human zinc finger E-box binding homeobox 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
ZEB1 (Zinc finger E-box-binding homeobox 1) acts as a transcriptional repressor that inhibits interleukin-2 (IL-2) gene expression. It modulates promoter activity of the ATP1A1 gene depending on cDNA quantity and cell type. ZEB1 represses E-cadherin promoters and induces epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. It also represses BCL6 transcription in the presence of CTBP1 and regulates neuronal differentiation by repressing RCOR1 transcription activation. Mutations in ZEB1 can lead to corneal dystrophy, posterior polymorphous corneal dystrophy, and Fuchs endothelial dystrophy type 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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