Thermo Fisher Scientific GCF Polyclonal Antibody
Rabbit polyclonal antibody targeting human GCF (TCF-9) for WB and IP applications. Recognizes residues 175–225 of GC-rich sequence DNA-binding factor. Supplied as liquid, unconjugated, 0.2 mg/mL, stored at 4°C. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 175 and 225 of human GC-rich sequence DNA-binding factor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
TCF-9 (transcription factor 9), also known as C2orf3 (chromosome 2 open reading frame 3), GCF (GC-rich sequence DNA-binding factor), or DNABF, is a 781-amino-acid nuclear protein that belongs to the GCF family. Widely expressed, GCF binds GC-rich sequences of beta-Actin, EGFR, and calcium-dependent protease (CANP) promoters.
GCF contains multiple phosphoserine and phosphothreonine residues, and two isoforms are produced due to alternative splicing events.
GCF is considered a candidate for susceptibility to dyslexia (DYX3), as both genes reside in close proximity on human chromosome 2. Chromosome 2 is the second largest human chromosome, consisting of approximately 237 million bases, encoding over 1,400 genes, and representing about 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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