Thermo Fisher Scientific Galectin 3 Polyclonal Antibody
Galectin 3 단백질을 검출하기 위한 Rabbit Polyclonal 항체로, WB, IHC, ICC, Flow Cytometry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액으로 4°C 또는 -20°C에서 보관 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | 1:50–1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human Galectin 3 (aa 1–180) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913245 |
Product Specific Information
- Positive Control: SiHa, mouse colon tissue, A431, LOVO, rat lung tissue, human colon cancer tissue, mouse testis tissue
- Subcellular Location: Cytoplasm, Nucleus, Secreted
Target Information
Galectin 3 is a galactose-specific lectin that binds IgE. It may mediate, with the alpha-3, beta-1 integrin, the stimulation by CSPG4 of endothelial cell migration. Together with DMBT1, it is required for terminal differentiation of columnar epithelial cells during early embryogenesis.
In the nucleus, it acts as a pre-mRNA splicing factor. It is involved in acute inflammatory responses, including neutrophil activation and adhesion, monocyte/macrophage chemoattraction, opsonization of apoptotic neutrophils, and activation of mast cells.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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