Thermo Fisher Scientific LYK5 Polyclonal Antibody, FITC
LYK5 단백질을 인식하는 FITC 결합 폴리클로날 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 인간 및 비인간 영장류 반응성, 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 연구용에 최적화되어 있습니다.
- 카탈로그번호
- STRAD-101-FITC
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 50–100 on human STE-20 related kinase adapter protein alpha |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LYK5; STE20-related Adaptor Protein (STRAD); FLJ90524.
Gene Map Locus: 17q23.3.
Members of the STE-20 like kinase family stimulate MAPK pathways by directly activating MAPKKK. STRAD is a novel pseudokinase member of this family with a STE-20 like kinase domain but lacking several residues required for catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. STRAD functions as an upstream activator of LKB1 and directs its sub-cellular localization by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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