
Thermo Fisher Scientific LYK5 Polyclonal Antibody, Biotin
LYK5 단백질을 인식하는 Biotin 결합 토끼 폴리클로날 항체. Western blot, IHC, ELISA, IP 등 다양한 응용 가능. Human 및 비인간 영장류 반응성. Affinity chromatography로 정제, -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 50–100 on human STE-20 related kinase adapter protein alpha (LYK5). |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, containing 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
LYK5 (STE20-related Adaptor Protein, STRAD; FLJ90524)
Gene locus: 17q23.3. Members of the STE-20-like kinase family stimulate MAPK pathways by directly activating MAPKKK. STRAD is a pseudokinase with a STE-20-like kinase domain but lacks several catalytic residues. It specifically binds to LKB1, regulating its tumor suppressor activity and subcellular localization. The STRAD–LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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