Thermo Fisher Scientific TRIP13 Polyclonal Antibody
TRIP13 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human에 반응하며 Mouse, Rat 등에서도 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며, 0.88 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 32–315 of Human TRIP13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.88 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549015 |
Product Specific Information
- Recommended positive controls: 293T, A431
- Predicted reactivity: Mouse (95%), Rat (96%), Xenopus laevis (84%), Dog (94%), Pig (95%), Chicken (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner.
TRIP13 (thyroid hormone receptor interactor 13), also known as 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1.
Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR.
The association of TRIP13 with HPV16 E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with two different isoforms produced by alternative splicing.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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