Thermo Fisher Scientific Phospho-MEF2D (Ser444) Polyclonal Antibody
Phospho-MEF2D (Ser444) 항체로 인간, 생쥐, 랫드 시료에 반응합니다. WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 사용 가능합니다. Rabbit Polyclonal 형식이며 Protein A로 정제되었습니다. -20°C 보관, 연구용 전용 시약입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human MEF2D around the phosphorylation site of Ser444 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The MEF2D gene belongs to the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family regulate muscle and neuronal cell differentiation and development, and are modulated by class II histone deacetylases. Fusions of MEF2D with DAZAP1 have been observed in acute lymphoblastic leukemia cell lines, suggesting a role in leukemogenesis. The encoded protein may also be implicated in Parkinson’s disease and myotonic dystrophy. Multiple transcript variants are produced through alternative splicing.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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