Thermo Fisher Scientific Phospho-MAPK11 (Thr180, Tyr182) Polyclonal Antibody
Phospho-MAPK11 (Thr180, Tyr182) 폴리클로날 항체로, 인간·생쥐·랫드 시료에서 MAPK11 인산화 상태 검출에 적합합니다. WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, Protein A 정제 및 고순도 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human MAPK11 around phosphorylation site Thr180+Tyr182 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAPK11 (p38 beta) is a serine/threonine kinase involved in various cellular processes and is activated by proinflammatory cytokines and environmental stress. The p38 MAPK beta protein is part of the MAP kinase family, which integrates multiple biochemical signals to regulate proliferation, differentiation, transcription, and development. MAPK11 is closely related to p38 MAP kinase and is activated through phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been identified as a substrate of this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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