Thermo Fisher Scientific GALNT6 Polyclonal Antibody
Human GALNT6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충 용액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GALNT6. Recombinant protein control fragment (Product # RP-90275) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641849 |
Product Specific Information
Immunogen sequence:
PWLKSLVSRK DHVLDLMLEA MNNLRDSMPK LQIRAPEAQQ TLFSINQSCL PGFYTPAELK PFWERPPQDP NAPGADGKAF QKSKWTPLET QEKEE
Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 80%
Target Information
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.
GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins.
They are characterized by:
- N-terminal transmembrane domain
- Stem region
- Lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif
- C-terminal ricin/lectin-like domain
GalNAc-Ts have different but overlapping substrate specificities and expression patterns.
The encoded protein can glycosylate fibronectin peptide in vitro and is expressed in fibroblast cell lines, suggesting involvement in oncofetal fibronectin synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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