Thermo Fisher Scientific CMTM1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human CMTM1 protein. Validated for IHC (Paraffin) with 1:20–1:50 dilution. Supplied as liquid, 0.2 mg/mL, in PBS with 40% glycerol. Suitable for research use in chemokine-related signaling and testis expression st...
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Applications
Tested Applications and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CMTM1. Recombinant protein control fragment (Product # RP-90925) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639928 |
Product Specific Information
- Immunogen sequence: TKMRTNLKRF LGVEVERKLS PAKDAY
- Highest antigen sequence identity: Mouse – 38%, Rat – 46%
Target Information
Chemokines are a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine-like factor superfamily (CKLFSF) share characteristics with both chemokine and transmembrane 4 superfamilies of signaling molecules.
CMTM1 (CKLF-like MARVEL transmembrane domain-containing protein 1), also known as CKLFSF1, is a 169 amino acid multi-pass membrane protein highly expressed in testis, suggesting a role in spermatogenesis or testicular development.
CMTM1 contains a CC-chemokine motif and four transmembrane segments. The gene encoding CMTM1 resides in a tight gene cluster on human chromosome 16 with CKLF, CMTM2, CMTM3, and CMTM4. There are at least sixteen isoforms of CMTM1 produced via alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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