Thermo Fisher Scientific Phospho-TrkA (Tyr791) Polyclonal Antibody
Phospho-TrkA (Tyr791) 특이적 폴리클로날 항체로, 인간·마우스·랫트 시료에서 TrkA 인산화 상태 검출에 적합. Western blot, IHC, ICC/IF 응용 가능. 고순도 Rabbit IgG 형태로 PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NTRK1 (Accession P04629), corresponding to amino acid residues around phosphorylated Tyr791 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816884 |
Product Specific Information
Antibody detects endogenous levels of TrkA only when phosphorylated at Tyr791.
Target Information
NTRK1 (TRKA) belongs to the neurotrophic factor family central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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