Thermo Fisher Scientific PGCB Polyclonal Antibody, Biotin
Thermo Fisher Scientific의 PGCB Polyclonal Antibody, Biotin은 Human, Mouse, Rat에 반응하며 Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합한 고품질 항체입니다. Biotin 결합 형태로 높은 특이성과 감도를 제공하며, 연구용으로 최적화되어 있습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes natriuretic peptide receptor B (NPR2), one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains:
- Extracellular ligand-binding domain
- Single membrane-spanning region
- Intracellular protein kinase homology domain
- Helical hinge region involved in oligomerization
- Carboxyl-terminal guanylyl cyclase catalytic domain
The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene cause acromesomelic dysplasia Maroteaux type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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