Thermo Fisher Scientific Cytokeratin 19 Monoclonal Antibody (1H6)
인간 KRT19 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 연구용 응용에 적합합니다. 세포 및 조직 수준에서 Cytokeratin 19 검출에 활용되며, 간 전이 식별 등 종양 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H6 |
| Immunogen | Purified recombinant fragment of human KRT19 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153960 |
Product Specific Information
MA5-15862 targets KRT19 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human KRT19 expressed in E. coli.
MA5-15862 detects KRT19, which has a predicted molecular weight of approximately 41 kDa.
Target Information
Cytokeratin 19 is part of a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides.
Cytokeratins range in molecular weight from 40–68 kDa and have isoelectric points between 4.9–7.8.
Human cytokeratins are numbered 1–20, and their expression patterns vary depending on epithelial type and degree of differentiation.
Cytokeratin subtype expression is used for distinguishing epithelial malignancies.
Cytokeratin antibodies assist in tumor differential diagnosis using immunohistochemistry and are useful in cytopathology and flow cytometry.
Cytokeratin 19 is not expressed in hepatocytes, making it useful for identifying liver metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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