Thermo Fisher Scientific HSP90 beta Monoclonal Antibody (5G4D2)
HSP90 beta 단백질을 검출하는 Mouse monoclonal antibody. Western blot, IHC, ICC/IF, Flow cytometry에 최적화. Human, Mouse, Rat 등 다양한 종에 반응. Protein A로 정제된 고순도 액상 항체로 안정적 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1–3 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5G4D2 |
| Immunogen | Purified recombinant fragment of human HSP90AB1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154459 |
Product Specific Information
MA5-15863 targets HSP90 beta in WB, IF, IHC, and Flow applications and shows reactivity with Human, Non-human primate, Mouse, and Rat samples.
Target Information
Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein induced under stress conditions but also one of the most abundant cellular proteins under non-stress conditions.
HSP90 proteins are highly conserved molecular chaperones with key roles in signal transduction, protein folding, degradation, and morphologic evolution. They associate with cochaperones to fold newly synthesized proteins or refold denatured proteins after stress.
HSP90 interacts with multiple intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and various kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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