Thermo Fisher Scientific GPCR GPR120 Polyclonal Antibody
GPR120(FFAR4) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, ELISA, Immunoprecipitation 등 다양한 응용에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 인체, 마우스, 랫트 반응성 보유.
- 카탈로그번호
- FFAR4-401AP
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific GPCR GPR120 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | N-epitope synthetic peptide within amino acid region 1–80 of human FFAR4 protein (GPR120) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
Activating ligands induce conformational changes leading to signaling via G-proteins and downstream effectors.
Studies have also shown mechanisms for negative regulation of GPCRs, which have major implications for cellular physiology and pharmacological research.
Two notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough), both major products in mental health and allergy treatment markets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항체의 구조 및 항원 관련 이미지: FFAR4-401AP_GPR120_Q5NUL3-2_Rabbit.svg, FFAR4-401AP_GPR120_Q5NUL3-2_Rabbit_PDP.jpeg)
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