
Thermo Fisher Scientific hnRNP M Polyclonal Antibody
Thermo Fisher Scientific의 hnRNP M Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 rabbit IgG 항체입니다. Western blot, IHC, ICC/IF, ELISA에 사용 가능하며 핵 및 핵소체 단백질 검출에 적합합니다. 액상 형태로 -20°C에서 보관합니다.
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- PA5121046
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 491–730 of human HNRNPM (NP_0059592) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.57 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914618 |
Product Specific Information
Positive test controls include BT-474, HL-60, Mouse thymus, and Rat liver.
The target is typically localized in the nucleus and nucleolus.
Immunogen sequence:
GFGLERMAAP IDRVGQTIER MGSGVERMGP AIERMGLSME RMVPAGMGAG LERMGPVMDR MATGLERMGA NNLERMGLER MGANSLERMG LERMGANSLE RMGPAMGPAL GAGIERMGLA MGGGGGASFD RAIEMERGNF GGSFAGSFGG AGGHAPGVAR KACQIFVRNL PFDFTWKMLK DKFNECGHVL YADIKMENGK SKGCGVVKFE SPEVAERACR MMNGMKLSGR EIDVRIDRNA
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).
hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and are associated with pre-mRNAs in the nucleus, influencing pre-mRNA processing and other aspects of mRNA metabolism and transport.
While all hnRNPs are present in the nucleus, some shuttle between the nucleus and cytoplasm.
The hnRNP M protein contains three quasi-RRM domains that bind RNAs and acts as a monomer of an N-acetylglucosamine-specific receptor involved in selective recycling of immature GlcNAc-bearing thyroglobulin molecules.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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