Thermo Fisher Scientific Chemerin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 17-163 of human RARRES2 (NP_002880.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Chemerin,uniProtId:Q99969-1,ncbiNodeId:9606,antigenRange:17-163,antigenLength:163,antigenImageFileName:PA5-121049_Chemerin_Q99969-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121049_Chemerin_Q99969-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.57 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914621

Product Specific Information

Positive test controls include: 293T, BT-474, HeLa, Mouse liver. The target is usually found in the following locations: Secreted.

Immunogen sequence: VGVAELTEAQ RRGLQVALEE FHKHPPVQWA FQETSVESAV DTPFPAGIFV RLEFKLQQTS CRKRDWKKPE CKVRPNGRKR KCLACIKLGS EDKVLGRLVH CPIETQVLRE AEEHQETQCL RVQRAGEDPH SFYFPGQFAF SKALPRS

Target Information

Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.