Thermo Fisher Scientific SMC2 Monoclonal Antibody (E1M)
SMC2 단백질을 인식하는 E1M 클론의 Mouse Monoclonal Antibody입니다. Western blot에 최적화되어 있으며, HeLa 세포를 양성 대조군으로 권장합니다. 단백질 A/G 정제, 1 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested Dilution 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E1M |
| Immunogen | Recombinant protein corresponding to aa 523–768 of human CAP-E |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087358 |
Product Specific Information
A suggested positive control for this product is HeLa cells.
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are members of the SMC (Structural Maintenance of Chromosome) family. They form a heterodimeric complex required for mitotic chromosome condensation, ensuring proper segregation of genetic information during cell division.
The hCAP-C/hCAP-E complex, known as condensin, interacts with phosphorylated Histone H3 to promote chromosome condensation.
Distinct distribution patterns of the two heterodimeric complexes in the interphase nucleus indicate independent roles during the cell cycle, suggesting involvement in different aspects of mitotic chromosome organization in human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(원본 이미지 파일명: MA1-12643_SMC2_O95347-1_House_mouse.svg, MA1-12643_SMC2_O95347-1_House_mouse_PDP.jpeg)
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