Thermo Fisher Scientific Natriuretic Peptide B/NPPB Monoclonal Antibody (NPPB/4493)
인간 NPPB 단백질을 인식하는 단클론 항체로, 심혈관 연구에 적합합니다. Immunohistochemistry 및 Peptide Array에 사용 가능하며, 단백질 정제는 Protein A/G 방식으로 수행되었습니다. 4°C에서 보관하며 동결 금지.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NPPB/4493 |
| Immunogen | Recombinant fragment of human NPPB (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. The protein undergoes two cleavage events—one intracellularly and another after secretion into the blood. Its biological actions include:
- Natriuresis and diuresis
- Vasorelaxation
- Inhibition of renin and aldosterone secretion
- Regulation of cardiovascular homeostasis
Elevated concentrations in the bloodstream are indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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