Thermo Fisher Scientific Natriuretic Peptide B/NPPB Monoclonal Antibody (NPPB/4493)
인간 NPPB 단백질을 인식하는 단클론 항체로, 심장 호르몬 관련 연구에 적합합니다. IHC(P), IHC(PFA), Peptide Array에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 4879-MSM3-P1ABX
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NPPB/4493 |
| Immunogen | Recombinant fragment of human NPPB (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and another after secretion into the blood. Its biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. Elevated levels of this protein in the bloodstream are indicative of heart failure. Mutations have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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