Thermo Fisher Scientific IL23A Polyclonal Antibody
Thermo Fisher Scientific의 IL23A Polyclonal Antibody는 mouse IL-23 p19 단백질을 인식하는 rabbit polyclonal 항체입니다. Western blot에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of mouse IL23 P19 (29–48aa, DWAQCQQLSRNLCMLAWNAH) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2884863 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
IL-23 is a heterodimeric cytokine composed of the p40 subunit of IL-12 disulfide-linked with a protein p19. The p19 subunit, like p35 of IL-12, is biologically inactive by itself. IL-23 interacts with IL-12Rβ1 and an additional receptor subunit IL-23R, which contains a STAT4 binding domain. IL-23 is secreted by activated mouse and human dendritic cells.
Mouse IL-23 differs from IL-12 in function: it does not induce significant IFN-γ production but strongly promotes proliferation of memory T cells and induces IL-17 production. Human IL-23 induces proliferation of memory T cells and moderate IFN-γ production compared to IL-12.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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