Thermo Fisher Scientific Phospho-RAB29 (Ser72) Polyclonal Antibody
RAB29의 Ser72 인산화 상태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 및 IHC(P) 검증 완료. Human, Mouse, Rat 반응성. 액상형, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Rab7L1 around the phosphorylation site of Rab29 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899266 |
Product Specific Information
Antibody detects endogenous levels of RAB7L1 only when phosphorylated at Rab29.
Target Information
Rab GTPase is a key regulator in vesicle trafficking, essential for maintaining the integrity of the endosome–trans-Golgi network structure. Together with LRRK2, it plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6-phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. It regulates neuronal process morphology in the intact central nervous system (CNS) and may play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi infection.
{ECO:0000269; PubMed:22042847, ECO:0000269; PubMed:24788816}
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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