Thermo Fisher Scientific Phospho-RAB29 (Thr71) Polyclonal Antibody
RAB29 단백질의 Thr71 인산화 부위를 특이적으로 인식하는 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 사람, 마우스, 랫트 반응성. PBS/50% 글리세롤 용액 형태로 제공되며 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Rab7L1 around the phosphorylation site of Rab29 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899267 |
Product Specific Information
This antibody detects endogenous levels of RAB7L1 only when phosphorylated at Rab29.
Target Information
Rab GTPase is a key regulator in vesicle trafficking, essential for maintaining the integrity of the endosome–trans-Golgi network structure. Together with LRRK2, it plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. It regulates neuronal process morphology in the intact central nervous system (CNS) and may play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi epithelial cell infection.
{ECO:0000269; PubMed:22042847, ECO:0000269; PubMed:24788816}.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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