Thermo Fisher Scientific SOX10 Recombinant Rabbit Monoclonal Antibody (SD204-04)
SOX10 단백질을 인식하는 재조합 토끼 단클론 항체로 높은 특이성과 민감도를 제공합니다. Western blot 및 IHC(P) 실험에 최적화되어 있으며, 로트 간 일관성과 동물 유래 성분이 없는 포뮬레이션을 특징으로 합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:800 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD204-04 |
| Immunogen | Synthetic peptide Human SOX10 aa 411–460 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809676 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
SOX10 is a member of the SOX (SRY-related HMG-box) transcription factor family, regulating embryonic development and cell fate determination. It functions as a transcriptional activator through complex formation with other proteins and acts as a nucleocytoplasmic shuttle. SOX10 plays a crucial role in neural crest and peripheral nervous system development.
Mutations in SOX10 are associated with Waardenburg-Shah and Waardenburg-Hirschsprung diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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