Thermo Fisher Scientific ErbB2 (HER-2) Recombinant Rabbit Monoclonal Antibody (7H3L20)
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ErbB2(HER2) 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot 및 Immunocytochemistry에 최적화. 높은 특이도와 재현성 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7H3L20 |
| Immunogen | Peptide corresponding to amino acids 33–46 of human ERBB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532480 |
Product Specific Information
- Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates ~25 kDa (light chain) and ~50 kDa (heavy chain) bands.
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits.
- Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase overexpressed in certain breast tumors. Herceptin, used in treatment of metastatic HER2-positive cancer, targets this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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