Thermo Fisher Scientific NCF2 Recombinant Rabbit Monoclonal Antibody (001)
Human NCF2 단백질을 인식하는 재조합 토끼 단클론 항체로, 높은 특이성과 일관된 로트 간 품질을 제공합니다. ELISA에 적합하며, 방부제가 포함되지 않은 PBS 용액 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 001 |
| Immunogen | Recombinant Human NCF2/NCF-2/P67phox Protein (Met1–Val526) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786386 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
This antibody specifically recognizes Human NCF2/NCF-2/P67phox.
Target Information
NCF2, NCF1, and a membrane-bound cytochrome b558 are required for activation of latent NADPH oxidase, essential for superoxide production.
Defects in NCF2 cause chronic granulomatous disease (autosomal recessive cytochrome-b-positive type 2, CGD2), a disorder where neutrophils and phagocytes cannot effectively kill ingested microbes, leading to severe bacterial and fungal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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