Thermo Fisher Scientific OASL Recombinant Rabbit Monoclonal Antibody (HL2399)
인간 OASL 단백질을 표적으로 하는 재조합 토끼 단일클론 항체. Western blot 및 IHC(파라핀) 실험에 적합. HEK293 세포에서 발현된 IgG 형 항체로, 단백질 A로 정제됨. PBS 용액 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2399 |
| Immunogen | Recombinant fragment of human OASL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093135 |
Target Information
2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly conserved family of interferon-induced enzymes.
The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains two ubiquitin-like domains.
p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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