Thermo Fisher Scientific Phospho-CENPA (Ser7) Polyclonal Antibody
Phospho-CENPA (Ser7) 폴리클로날 항체로, 인간·마우스·랫트 시료에서 Ser7 인산화된 CENPA를 검출 가능. Western blot 및 IHC(P) 적용. 고순도 정제, 액상 형태, -20°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CENPA (Accession P49450), corresponding to amino acid residues around phosphorylated Ser7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816058 |
Product Specific Information
Antibody detects endogenous levels of CENPA only when phosphorylated at Ser7.
Target Information
Centromeres are differentiated chromosomal domains that specify the mitotic behavior of chromosomes.
CENPA encodes a centromere protein containing a histone H3-related histone fold domain required for targeting to the centromere.
CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure, replacing one or both copies of conventional histone H3 in the (H3-H4)₂ tetrameric core of the nucleosome particle.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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