Thermo Fisher Scientific CaV3.1 Polyclonal Antibody
CaV3.1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
Western Blot (WB)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in human CACNA1G |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553976 |
Product Specific Information
- Detects endogenous CaV3.1 protein at a molecular weight of approximately 262 kDa.
- Purity >95% by SDS-PAGE.
Target Information
Voltage-dependent Ca²⁺ channels mediate calcium entry into excitable cells in response to membrane depolarization. These channels are involved in processes such as muscle contraction, hormone and neurotransmitter release, and gene expression.
They are multimeric complexes composed of:
- α1 subunit
- intracellular β subunit
- disulfide-linked α2/δ subunit
- transmembrane γ subunit
Ca²⁺ currents are classified as L-, N-, T-, P-, Q-, and R-types based on their biophysical and pharmacologic properties.
T-type Ca²⁺ currents activate and inactivate more rapidly and at more negative membrane potentials than other types, enhancing odor sensitivity by lowering the threshold for spike generation in olfactory receptor cells (ORCs).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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