Thermo Fisher Scientific CaV3.1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000
• Publications: -

Product Specifications

Product Specific Information

• Detects endogenous CaV3.1 protein at a molecular weight of approximately 262 kDa.
• Purity >95% by SDS-PAGE.

Target Information

Voltage-dependent Ca²⁺ channels mediate calcium entry into excitable cells in response to membrane depolarization. These channels are involved in processes such as muscle contraction, hormone and neurotransmitter release, and gene expression.
They are multimeric complexes composed of:

• α1 subunit
• intracellular β subunit
• disulfide-linked α2/δ subunit
• transmembrane γ subunit

Ca²⁺ currents are classified as L-, N-, T-, P-, Q-, and R-types based on their biophysical and pharmacologic properties.
T-type Ca²⁺ currents activate and inactivate more rapidly and at more negative membrane potentials than other types, enhancing odor sensitivity by lowering the threshold for spike generation in olfactory receptor cells (ORCs).

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.