Thermo Fisher Scientific PIGA Polyclonal Antibody
PIGA 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 등 다양한 종에 반응하며, Affinity chromatography로 정제된 고품질 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
Tested Application
- Western Blot (WB): 1:1,000–1:3,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PIGA (Accession P37287), corresponding to amino acid residues T446–R484 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853337 |
Product Specific Information
Antibody detects endogenous levels of total PIGA.
Target Information
This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor.
The GPI anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface.
Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene.
Alternate splice variants have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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