Thermo Fisher Scientific HDAC6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 836-1104 of human HDAC6 (NP_006035.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HDAC6,uniProtId:Q9UBN7-1,ncbiNodeId:9606,antigenRange:836-1104,antigenLength:1215,antigenImageFileName:PA5-120113_HDAC6_Q9UBN7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120113_HDAC6_Q9UBN7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.36 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913685

Product Specific Information

Positive test controls include: Rat liver. The target is usually found in the following locations: Cell projection, Cytoplasm, Nucleus, Perikaryon, axon, dendrite.

Immunogen sequence: VMKVEDREGP SSSKLVTKKA PQPAKPRLAE RMTTREKKVL EAGMGKVTSA SFGEESTPGQ TNSETAVVAL TQDQPSEAAT GGATLAQTIS EAAIGGAMLG QTTSEEAVGG ATPDQTTSEE TVGGAILDQT TSEDAVGGAT LGQTTSEEAV GGATLAQTTS EAAMEGATLD QTTSEEAPGG TELIQTPLAS STDHQTPPTS PVQGTTPQIS PSTLIGSLRT LELGSESQGA SESQAPGEEN LLGEAAGGQD MADSMLMQGS RGLTDQAIF

Target Information

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.