Thermo Fisher Scientific RAD51 Polyclonal Antibody
RAD51 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 생쥐, 랫트 반응성. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. DNA 복구 연구에 활용 가능. 동결건조 형태로 제공, -20°C 보관.
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Thermo Fisher Scientific RAD51 Polyclonal Antibody
Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human Rad51 recombinant protein (Position: M1–E258) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2747023 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recombination. It binds to single- and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments essential for the homology search and strand exchange. Mutations in the gene can result in breast cancer, mirror movements 2, and Fanconi anemia.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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