Thermo Fisher Scientific CARD11 Monoclonal Antibody (B.472.3)
CARD11 단백질을 인식하는 Rabbit monoclonal 항체로, Western blot에 최적화되어 있습니다. Human 및 Mouse 시료에 반응하며, NF-kappaB 활성화 연구에 유용합니다. 고순도 친화 크로마토그래피 정제 및 안정한 액상 형태로 제공됩니다.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B.472.3 |
| Immunogen | Synthetic peptide corresponding to residues surrounding threonine 175 of CARD11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 344 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 50% glycerol, 100 µg/mL BSA |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10983903 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, functioning as a molecular scaffold for multiprotein complex assembly at specialized plasma membrane regions. It is also part of the CARD protein family, characterized by a caspase-associated recruitment domain (CARD). This protein shares structural similarity with CARD14 and interacts specifically with BCL10, a regulator of apoptosis and NF-kappaB activation. Expression of this protein in cells activates NF-kappaB and induces phosphorylation of BCL10.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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