Thermo Fisher Scientific CALHM1/FAM26C Polyclonal Antibody
CALHM1/FAM26C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Protein A 정제, -20°C 보관.
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Thermo Fisher Scientific CALHM1/FAM26C Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CALHM1/FAM26C, amino acids 161–260 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons and the presence of senile plaques composed of aggregated amyloid-beta (Abeta) peptides produced by endoproteolysis of the amyloid precursor protein (APP).
CALHM1 (Calcium Homeostasis Modulator 1) is a multipass transmembrane glycoprotein that regulates cytosolic Ca²⁺ concentration and Abeta levels. Some studies suggest CALHM1 is associated with AD risk, while others report no direct link. CALHM1 may modulate Ca²⁺-dependent proteolysis of APP through control of cytosolic Ca²⁺ levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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