
Thermo Fisher Scientific FISH Polyclonal Antibody
다양한 면역학적 응용(IHC, ICC, ELISA)에 적합한 Rabbit Polyclonal Antibody. Human, Mouse, Rat 반응성. KLH 결합 합성 펩타이드 면역원 사용. Protein A 정제, 1 mg/mL 농도. 연구용 전용 제품으로 높은 특이성과 재현성 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human FISH, amino acids 261–360 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation, and invasiveness of some cancer cells.
Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs), and phosphoinositides.
Acts as an organizer protein enabling NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and localization.
In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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