Thermo Fisher Scientific Ferritin Heavy Chain Recombinant Rabbit Monoclonal Antibody (9H17L10)
Ferritin Heavy Chain(FTH1)을 인식하는 재조합 토끼 단클론 항체로, WB 및 ICC/IF에 적합합니다. 높은 특이성과 재현성을 제공하며, 로트 간 일관성이 우수합니다. 인간, 생쥐, 랫드에 반응하며, 단기 4℃, 장기 -20℃ 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9H17L10 |
| Immunogen | Peptides corresponding to Human FTH1 (aa 41–54, 77–95) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% Sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633038 |
Product Specific Information
This antibody is predicted to react with Monkey, Dog, Cat, and Pig.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening of individual clones to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
FTH1 (Ferritin Heavy Chain)
FTH1 encodes the heavy subunit of ferritin, the primary intracellular iron storage protein in both prokaryotes and eukaryotes. Ferritin consists of 24 subunits of heavy and light chains, and variation in subunit composition influences iron uptake and release rates across tissues. Its main function is to store iron in a soluble and non-toxic form. Defects in ferritin proteins are linked to several neurodegenerative diseases. Multiple pseudogenes and alternatively spliced transcript variants have been identified, though their biological roles remain uncertain.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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