Thermo Fisher Scientific Phospho-RSK3 (Ser360) Polyclonal Antibody
RSK3 단백질의 Ser360 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 실험에 적합. 고순도 액상 형태로 PBS/glycerol buffer에 보존되며, 연구용으로 사용.
- 카탈로그번호
- PA5105917
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: 참고 문헌 없음
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: 참고 문헌 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPS6KA2 (Accession Q15349), corresponding to amino acid residues around phosphorylated Ser360 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817316 |
Product Specific Information
Antibody detects endogenous levels of RSK3 only when phosphorylated at Ser360.
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It functions as a signal-transducing intermediate in the cellular response to several growth factors. RPS6KA2 is expressed in many tissues, with higher levels in lung and skeletal muscle.
The p90 ribosomal S6 kinases (RSK1–4) are downstream members of the ERK/MAPK cascade. Loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may influence G-protein coupled signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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