Thermo Fisher Scientific Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Monoclonal Antibody (SOD1, 3924)
Human SOD1 단백질을 표적으로 하는 Mouse monoclonal antibody로, Western blot 및 IHC(P) 등 다양한 응용에 적합. Recombinant fragment(aa14-148)를 면역원으로 사용. 200 µg/mL 농도의 액상 형태로 제공되며, 4°C 보관.
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- 6647-MSM4-P0
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2–4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SOD1, 3924 |
| Immunogen | Recombinant fragment (around aa14–148) of human SOD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at room temperature for 20 min.
Target Information
SOD1 (Superoxide Dismutase 1) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body.
This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert harmful superoxide radicals to molecular oxygen and hydrogen peroxide.
The other isozyme is a mitochondrial protein.
Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.
Rare transcript variants have been reported for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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