Thermo Fisher Scientific Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Monoclonal Antibody (SOD1, 3924)
SOD1 단백질을 인식하는 Mouse monoclonal 항체로, Western blot, IHC, Peptide Array에 사용 가능. Human 시료에 반응하며, 단백질 산화 스트레스 연구 및 ALS 관련 연구에 적합. 단백질 A/G 정제, PBS buffer, 무보존제, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SOD1, 3924 |
| Immunogen | Recombinant fragment (around aa14–148) of human SOD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C or –80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- For formalin-fixed tissues, heat tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, then cool at room temperature for 20 min.
Target Information
SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This soluble cytoplasmic protein acts as a homodimer to convert harmful superoxide radicals into molecular oxygen and hydrogen peroxide. The other isozyme is mitochondrial. Mutations in this gene are associated with familial amyotrophic lateral sclerosis (ALS). Rare transcript variants have also been reported.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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