Thermo Fisher Scientific Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) Monoclonal Antibody (SOD1, 3924)
Human SOD1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, Peptide array에 사용 가능. Recombinant fragment(aa14-148)를 면역원으로 사용하며 Protein A/G로 정제됨. 항산화 효소 연구 및 ALS 관련 연구에 적합.
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Thermo Fisher Scientific Superoxide Dismutase 1 (SOD1) Monoclonal Antibody (SOD1, 3924)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SOD1, 3924 |
| Immunogen | Recombinant fragment (around aa14–148) of human SOD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at room temperature for 20 minutes.
Target Information
SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein that acts as a homodimer to convert harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is mitochondrial.
Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS). Rare transcript variants have been reported for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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