Thermo Fisher Scientific PMP22 Monoclonal Antibody (OTI5D1), TrueMAB
PMP22 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 IHC(P) 검증 완료. 사람, 생쥐, 랫트 반응성. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 말초신경 수초 구조 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D1 |
| Immunogen | Full length human recombinant protein of human PMP22 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Peripheral Myelin Protein 22 (PMP22) is a 160 amino acid glycoprotein and a member of the claudin family, playing an essential role in the structure of peripheral nerve myelin.
Genetic irregularities in PMP22 are associated with hereditary demyelinating neuropathies.
PMP22 is present in the compact myelin of adult human peripheral nerves, and its distribution resembles that of Myelin Protein Zero (P0).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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