Thermo Fisher Scientific NOXA Monoclonal Antibody (114C307.1)
Thermo Fisher Scientific의 NOXA 단클론 항체(114C307.1)는 인간, 마우스, 랫트에 반응하며 p53 관련 세포사멸 연구에 적합합니다. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용 가능. Protein G 정제, 액상 형태, 1.0 mg/mL 농도.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:20–1:1,000 |
| Flow Cytometry (Flow) | 1 µg/million cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 114C307.1 |
| Immunogen | Human Noxa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1077295 |
Product Specific Information
Suggested positive control: antigen standard for PMAIP1 (transient overexpression lysate), RL-7, Jurkat.
Target Information
Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA. A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptotic proteins. Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins. X-ray irradiation increases p53-dependent Noxa mRNA and protein levels. Noxa, when ectopically expressed, interacts with anti-apoptotic Bcl-2 family members, resulting in activation of caspase-9. Noxa, like PUMA, localizes to mitochondria and induces apoptosis in response to p53. Noxa and PUMA may represent direct mediators of p53-induced apoptosis. Increased levels of p53 and its target gene Noxa have been found in impaired tumor development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific DNMT3A Monoclonal Antibody (64B814.1)
572,900원
Thermo Fisher Scientific
Thermo Fisher Scientific TRF2 Monoclonal Antibody (4A794.15)
780,100원
Thermo Fisher Scientific
Thermo Fisher Scientific NOXA Monoclonal Antibody (114C307.1)
646,200원
Thermo Fisher Scientific
Thermo Fisher Scientific RAD9 Monoclonal Antibody (93A535)
628,600원
Thermo Fisher Scientific
Thermo Fisher Scientific CD14 Monoclonal Antibody (18D11)
806,500원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|