Thermo Fisher Scientific LRRK2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Frozen) (IHC (F))

1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues (L(946) K R K R K I L S S D D S L R S S(962) of human LRRK2 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRRK2,uniProtId:Q5S007-1,ncbiNodeId:9606,antigenRange:946-962,antigenLength:2527,antigenImageFileName:PA1-18254_LRRK2_Q5S007-1_Sheep.svg,antigenImageFileNamePDP:PA1-18254_LRRK2_Q5S007-1_Sheep_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1076528

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent.

Target Information

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson`s disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.