Thermo Fisher Scientific LRRK2 Polyclonal Antibody
LRRK2 단백질을 인식하는 Sheep Polyclonal 항체로, 인간 시료에 반응합니다. IHC(F)에서 1:500 희석으로 사용 가능하며, 동결 건조 형태로 제공됩니다. 파킨슨병 연구 등 LRRK2 관련 연구에 적합합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Immunohistochemistry (Frozen) (IHC (F)): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues L(946)-S(962) of human LRRK2 protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076528 |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material. After reconstitution, keep aliquots at -20°C for higher stability, and at 4°C with an appropriate antibacterial agent.
Target Information
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson’s disease. LRRK2 belongs to the leucine-rich repeat kinase family and encodes a protein containing ankyrin repeats, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is largely cytoplasmic but also associates with the mitochondrial outer membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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