Thermo Fisher Scientific FGR Polyclonal Antibody
FGR 단백질을 검출하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. 인간, 마우스, 랫트 반응성으로 Western Blot에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보존됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human FGR (UniProt ID: P09769-1, antigen range: 403–423) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635236 |
Product Specific Information
This antibody detects endogenous levels of total FGR protein.
Target Information
FGR is a SRC-related kinase present in hematopoietic cells. It signals within multiple pathways, including integrin and downstream chemokine/cytokine receptor pathways. The protein includes N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2/SH3 domains that mediate protein-protein interactions. FGR localizes to plasma membrane ruffles and negatively regulates cell migration and adhesion triggered by beta-2 integrin signaling. Epstein-Barr virus infection can cause overexpression of this protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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