Thermo Fisher Scientific Glucagon Receptor Recombinant Rabbit Monoclonal Antibody (21H1L9)

Applications

Tested Dilution

Publications

Western Blot (WB)

2.5 µg/mL

-

Immunocytochemistry (ICC/IF)

5 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Monoclonal

Type

Antibody

Clone

21H1L9

Immunogen

Peptide corresponding to human Glucagon Receptor (aa198-aa211) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Glucagon Receptor,uniProtId:P47871-1,ncbiNodeId:9606,antigenRange:198-211,antigenLength:477,antigenImageFileName:702602_Glucagon_Receptor_P47871-1_Rabbit.svg,antigenImageFileNamePDP:702602_Glucagon_Receptor_P47871-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2716883

Product Specific Information

This antibody is predicted to react with Monkey, Horse, Bovine, Dog

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Target Information

Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.