Thermo Fisher Scientific Glucagon Receptor Recombinant Rabbit Monoclonal Antibody (21H1L9)
Thermo Fisher의 Glucagon Receptor Rabbit Monoclonal Antibody (21H1L9)은 인간 및 랫트 반응성을 가지며, WB와 ICC/IF에 사용 가능. 높은 특이성과 일관성을 제공하는 재조합 항체로, 동물 유래 성분이 없음. 혈당 조절 관련 Glucagon Receptor 연구에 최적화.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 21H1L9 |
| Immunogen | Peptide corresponding to human Glucagon Receptor (aa198–aa211) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2716883 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, Bovine, and Dog.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in regulating blood glucose levels and homeostasis. They control hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis, and mediate physiological responses to fasting. Ligand binding induces conformational changes that activate G-protein signaling and downstream effectors.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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