
Thermo Fisher Scientific HBS1L Monoclonal Antibody (OTI1G7), TrueMAB
인간 HBS1L 단백질(aa 1-260)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 최적화되어 있으며, 동결건조 형태로 제공. PBS 완충액(8% 트레할로스) 포함, -20°C 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–260 of human HBS1L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The HBS1L gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues, with highest levels in heart and skeletal muscle.
The intergenic region between HBS1L and MYB is a quantitative trait locus (QTL) influencing fetal hemoglobin levels, erythrocyte and platelet counts, and hemoglobin content.
Polymorphisms in this region are associated with fetal hemoglobin levels and clinical severity in sickle cell disease and beta-thalassemia/Hemoglobin E.
Multiple alternatively spliced transcript variants encoding different protein isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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