Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Synaptophysin 단백질을 인식하는 기니피그 폴리클로날 항체로, 신경세포 말단 및 신경내분비 종양 마커 연구에 활용됩니다. WB 및 IHC(P) 검증 완료. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Guinea pig / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from rat Synaptophysin conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Synaptophysin.
Target Information
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in nearly all neurons. It contains four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting involvement in synaptic vesicle endocytosis. It also regulates short-term and long-term synaptic plasticity. Synaptophysin is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in X-linked mental retardation (syndrome 96).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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