Thermo Fisher Scientific PKM1 Monoclonal Antibody (OTI4E8), TrueMAB
인간 PKM1 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 IHC(P) 실험에 적합. 합성 펩타이드 면역원 사용, 고순도 친화 크로마토그래피 정제. 안정한 액상 형태로 -20°C 보관 권장. 연구용으로만 사용 가능.
- 판매단위
- pk
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Thermo Fisher Scientific PKM1 Monoclonal Antibody (OTI4E8), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E8 |
| Immunogen | Synthetic peptide sequence corresponding to the region encoded by PKM gene M1 isoform |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Synthetic peptide sequence: LVRASSHSTD LMEAMAMGSV
Target Information
PKM1 encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate.
This protein interacts with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones.
It also binds Opa protein, a bacterial outer membrane protein involved in gonococcal adherence and invasion of human cells, suggesting a potential role in bacterial pathogenesis.
Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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