Thermo Fisher Scientific Acidic Cytokeratin Monoclonal Antibody (OTI8F5), TrueMAB
인간 세포에서 산성 세포각질을 검출하는 단클론 항체로, IHC(파라핀 절편) 실험에 최적화됨. Rat IgG 기반으로 합성 펩타이드 면역원 사용. 1 mg/mL 농도의 액상 형태이며, 암 연구 및 세포 분화 분석에 유용함.
- 카탈로그번호
- TA190168
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F5 |
| Immunogen | Synthetic peptide corresponding to the conserved region of human type I (Acidic) keratins (including KRT9–KRT20). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Synthetic peptide sequence: EKVTMQNLND RLASYLDKVR ALEEAN
Target Information
Cytokeratin pan belongs to a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides.
Cytokeratins have molecular weights between 40–68 kDa and isoelectric points between pH 4.9–7.8.
Each cytokeratin subtype is numbered 1–20 and shows distinct expression patterns depending on epithelial type and differentiation stage.
These patterns are valuable for distinguishing epithelial malignancies and are widely used in tumor diagnosis, cytopathology, and flow cytometry.
Keratins serve as useful markers in cancer research and tumor differentiation studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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